Clinical implications of p53 autoantibodies in the sera of patients with non-small-cell lung cancer.
Identifieur interne : 003A16 ( Main/Exploration ); précédent : 003A15; suivant : 003A17Clinical implications of p53 autoantibodies in the sera of patients with non-small-cell lung cancer.
Auteurs : T. Mitsudomi [Japon] ; S. Suzuki ; Y. Yatabe ; M. Nishio ; M. Kuwabara ; K. Gotoh ; S. Hatooka ; M. Shinoda ; M. Suyama ; M. Ogawa ; T. Takahashi ; Y. Ariyoshi ; T. TakahashiSource :
- Journal of the National Cancer Institute [ 0027-8874 ] ; 1998.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse de survie, Autoanticorps (sang), Carcinome pulmonaire non à petites cellules (), Carcinome pulmonaire non à petites cellules (anatomopathologie), Carcinome pulmonaire non à petites cellules (immunologie), Femelle, Humains, Modèles de hasards proportionnels, Mâle, Noyau de la cellule (métabolisme), Pronostic, Protéine p53 suppresseur de tumeur (immunologie), Protéine p53 suppresseur de tumeur (métabolisme), Sujet âgé, Sujet âgé de 80 ans ou plus, Technique de Western, Test ELISA, Tumeurs du poumon (), Tumeurs du poumon (anatomopathologie), Tumeurs du poumon (immunologie), Valeur prédictive des tests.
- MESH :
- anatomopathologie : Carcinome pulmonaire non à petites cellules, Tumeurs du poumon.
- immunologie : Carcinome pulmonaire non à petites cellules, Protéine p53 suppresseur de tumeur, Tumeurs du poumon.
- métabolisme : Noyau de la cellule, Protéine p53 suppresseur de tumeur.
- sang : Autoanticorps.
- Adulte, Adulte d'âge moyen, Analyse de survie, Carcinome pulmonaire non à petites cellules, Femelle, Humains, Modèles de hasards proportionnels, Mâle, Pronostic, Sujet âgé, Sujet âgé de 80 ans ou plus, Technique de Western, Test ELISA, Tumeurs du poumon, Valeur prédictive des tests.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Autoantibodies (blood), Blotting, Western, Carcinoma, Non-Small-Cell Lung (immunology), Carcinoma, Non-Small-Cell Lung (pathology), Carcinoma, Non-Small-Cell Lung (surgery), Cell Nucleus (metabolism), Enzyme-Linked Immunosorbent Assay, Female, Humans, Lung Neoplasms (immunology), Lung Neoplasms (pathology), Lung Neoplasms (surgery), Male, Middle Aged, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Survival Analysis, Tumor Suppressor Protein p53 (immunology), Tumor Suppressor Protein p53 (metabolism).
- MESH :
- chemical , blood : Autoantibodies.
- immunology : Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Tumor Suppressor Protein p53.
- metabolism : Cell Nucleus, Tumor Suppressor Protein p53.
- pathology : Carcinoma, Non-Small-Cell Lung, Lung Neoplasms.
- surgery : Carcinoma, Non-Small-Cell Lung, Lung Neoplasms.
- Adult, Aged, Aged, 80 and over, Blotting, Western, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Survival Analysis.
Abstract
The presence of autoantibodies to p53 protein has been associated with the presence of p53 (also known as TP53) gene mutations in primary tumors and with poor prognosis. This study was undertaken to determine the clinical significance of p53 autoantibodies in patients with non-small-cell lung cancer (NSCLC).
DOI: 10.1093/jnci/90.20.1563
PubMed: 9790550
Affiliations:
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Mitsudomi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Aichi Cancer Center Hospital, Nagoya</wicri:regionArea><wicri:noRegion>Nagoya</wicri:noRegion></affiliation></author><author><name sortKey="Suzuki, S" sort="Suzuki, S" uniqKey="Suzuki S" first="S" last="Suzuki">S. Suzuki</name></author><author><name sortKey="Yatabe, Y" sort="Yatabe, Y" uniqKey="Yatabe Y" first="Y" last="Yatabe">Y. Yatabe</name></author><author><name sortKey="Nishio, M" sort="Nishio, M" uniqKey="Nishio M" first="M" last="Nishio">M. Nishio</name></author><author><name sortKey="Kuwabara, M" sort="Kuwabara, M" uniqKey="Kuwabara M" first="M" last="Kuwabara">M. Kuwabara</name></author><author><name sortKey="Gotoh, K" sort="Gotoh, K" uniqKey="Gotoh K" first="K" last="Gotoh">K. Gotoh</name></author><author><name sortKey="Hatooka, S" sort="Hatooka, S" uniqKey="Hatooka S" first="S" last="Hatooka">S. Hatooka</name></author><author><name sortKey="Shinoda, M" sort="Shinoda, M" uniqKey="Shinoda M" first="M" last="Shinoda">M. Shinoda</name></author><author><name sortKey="Suyama, M" sort="Suyama, M" uniqKey="Suyama M" first="M" last="Suyama">M. Suyama</name></author><author><name sortKey="Ogawa, M" sort="Ogawa, M" uniqKey="Ogawa M" first="M" last="Ogawa">M. Ogawa</name></author><author><name sortKey="Takahashi, T" sort="Takahashi, T" uniqKey="Takahashi T" first="T" last="Takahashi">T. Takahashi</name></author><author><name sortKey="Ariyoshi, Y" sort="Ariyoshi, Y" uniqKey="Ariyoshi Y" first="Y" last="Ariyoshi">Y. Ariyoshi</name></author><author><name sortKey="Takahashi, T" sort="Takahashi, T" uniqKey="Takahashi T" first="T" last="Takahashi">T. 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This study was undertaken to determine the clinical significance of p53 autoantibodies in patients with non-small-cell lung cancer (NSCLC).</div></front></TEI><affiliations><list><country><li>Japon</li></country></list><tree><noCountry><name sortKey="Ariyoshi, Y" sort="Ariyoshi, Y" uniqKey="Ariyoshi Y" first="Y" last="Ariyoshi">Y. Ariyoshi</name><name sortKey="Gotoh, K" sort="Gotoh, K" uniqKey="Gotoh K" first="K" last="Gotoh">K. Gotoh</name><name sortKey="Hatooka, S" sort="Hatooka, S" uniqKey="Hatooka S" first="S" last="Hatooka">S. Hatooka</name><name sortKey="Kuwabara, M" sort="Kuwabara, M" uniqKey="Kuwabara M" first="M" last="Kuwabara">M. Kuwabara</name><name sortKey="Nishio, M" sort="Nishio, M" uniqKey="Nishio M" first="M" last="Nishio">M. Nishio</name><name sortKey="Ogawa, M" sort="Ogawa, M" uniqKey="Ogawa M" first="M" last="Ogawa">M. Ogawa</name><name sortKey="Shinoda, M" sort="Shinoda, M" uniqKey="Shinoda M" first="M" last="Shinoda">M. Shinoda</name><name sortKey="Suyama, M" sort="Suyama, M" uniqKey="Suyama M" first="M" last="Suyama">M. Suyama</name><name sortKey="Suzuki, S" sort="Suzuki, S" uniqKey="Suzuki S" first="S" last="Suzuki">S. Suzuki</name><name sortKey="Takahashi, T" sort="Takahashi, T" uniqKey="Takahashi T" first="T" last="Takahashi">T. Takahashi</name><name sortKey="Takahashi, T" sort="Takahashi, T" uniqKey="Takahashi T" first="T" last="Takahashi">T. Takahashi</name><name sortKey="Yatabe, Y" sort="Yatabe, Y" uniqKey="Yatabe Y" first="Y" last="Yatabe">Y. Yatabe</name></noCountry><country name="Japon"><noRegion><name sortKey="Mitsudomi, T" sort="Mitsudomi, T" uniqKey="Mitsudomi T" first="T" last="Mitsudomi">T. Mitsudomi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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